Job Dekker is an Investigator of the Howard Hughes Medical Institute and Professor in the Department of Systems Biology at the University of Massachusetts Chan Medical School. His laboratory studies how genomes are folded in three dimensions. His work has led to insights into the formation of chromatin loops involved in long-range gene regulation, the organization of the interphase nucleus, the structure of metaphase chromosomes, and general folding principles of genomes. His group pioneered the use of genome folding data for genome assembly. Recently, his lab started exploring chromosome folding mechanisms in organisms with unusual genome organizations, such as dinoflagellates.